The Fire Department and the U.S. Coast Guard say the girl was in the water for 20 minutes Sunday before being pulled to safety conscious and responsive.
She was transported to Marin General Hospital but her condition wasn't immediately available.
The San Francisco Chronicle reports that it's not known if the girl jumped or fell.
Officials say about 25 people per year die in jumps from the bridge, roughly 200 feet above the water.
In March, a 17-year-old boy survived after leaping from the bridge. Officials don't believe it was a suicide attempt.